Staff Research Associate II

Founded in 1965, UC Irvine is a member of the prestigious Association of American Universities and is ranked among the nation's top 10 public universities by U.S. News & World Report. The campus has produced five Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UC Irvine has more than 36,000 students and offers 224 degree programs. It's located in one of the world's safest and most economically vibrant communities and is Orange County's second-largest employer, contributing $7 billion annually to the local economy and $8 billion statewide.

To learn more about UC Irvine, visit www.uci.edu.

The Department of Radiation Oncology is committed to providing leading-edge, compassionate clinical care, pioneering new therapies for patients, ushering the latest treatments from the laboratory to the clinic and training the next generation of leaders in the specialty.

The incumbent carry out technical responsibilities specified in a number of federally (NIH, NASA) sponsored grant proposals in the field of radiation and chemotherapy-induced brain injury. He/She will be largely responsible for conducting tumor studies in select mouse models, with a major emphasis on orthotopic brain tumor implantation with and without radiosensitizing nanoparticle conjugates, requiring skills in stereotactic live animal surgery, conformal irradiation procedures and imaging. Additional lab duties will involve a variety of procedures necessary for the preparation, imaging and analysis of brain and tumor tissues for immune profiling and in generating fixed and frozen tissue sections used to quantify various CNS and immune specific endpoints. These duties will include tissue blocking, cryostat sectioning, confocal microscopy, flow cytometry and data quantification using in house/core software platforms. Another important job duty will entail behavioral testing using video recording and specialized analysis software and to maintain breeding colonies and genotyping of transgenic mice over time. Mouse colony maintenance and behavioral testing will be high priorities for this position and will be the secondary job functions expected on a daily basis. Lastly, the position will be required to maintain accurate research records, perform standard statistical analyses and support general lab duties such as reagent preparation, cleaning and dishware. Familiarity with some but not all of the foregoing will be a prerequisite of employment.

SPECIAL CONDITIONS:
Due to the nature of ongoing experiments, flexibility in the work schedule is a must, as some experiments will require work at either abnormal hours or over weekends. The candidate MUST be willing to work with animals and radiation sources. Also due to the nature of funded projects the successful candidate should be willing to travel. Travel may be as frequent as two times a year. All studies performed will be in accordance with UCI radiation safety and institutional animal (IUCAC) approval standards.

Required:

• Behavioral testing involving rodents
• Familiarity with small animal (mouse) handling
• Laboratory experience utilizing the techniques and methods itemized above
• Experience working independently
• Experience in assisting, testing and standardizing immunohistological techniques
• Experience in tissue handling and cryostat sectioning
• Experience in use of confocal and fluorescent microscopic techniques to assess neural stem/precursor cell populations
• Experience in use of routine statistical, data plotting programs
• Previous experience with basic laboratory procedures and practices

Preferred:

• Radiobiology background.

Special Conditions:

• Willingness to travel.

Total Rewards

In addition to the salary range listed below, we offer a wealth of benefits to make working at UCI even more rewarding. These benefits may include medical insurance, sick and vacation time, retirement savings plans, and access to a number of discounts and perks. Please utilize the links listed here to learn more about our compensation practices and benefits.

Conditions of Employment:

The University of California, Irvine (UCI) seeks to provide a safe and healthy environment for the entire UCI community. As part of this commitment, all applicants who accept an offer of employment must comply with the following conditions of employment:

• Background Check and Live Scan
• Employment Misconduct*
• Legal Right to work in the United States
• Vaccination Policies
• Smoking and Tobacco Policy
• Drug Free Environment

*Misconduct Disclosure Requirement: As a condition of employment, the final candidate who accepts a conditional offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; received notice of any allegations or are currently the subject of any administrative or disciplinary proceedings involving misconduct; have left a position after receiving notice of allegations or while under investigation in an administrative or disciplinary proceeding involving misconduct; or have filed an appeal of a finding of misconduct with a previous employer.

The following additional conditions may apply, some of which are dependent upon business unit or job specific requirements.

• California Child Abuse and Neglect Reporting Act
• E-Verify
• Pre-Placement Health Evaluation

Details of each policy may be reviewed by visiting the following page - https://hr.uci.edu/new-hire/conditions-of-employment.php

Closing Statement:

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC Anti-Discrimination Policy.

We are committed to attracting and retaining a diverse workforce along with honoring unique experiences, perspectives, and identities. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable, and welcoming.

UCI provides reasonable accommodations for applicants with disabilities upon request. For more information, please contact Human Resources at (949) 824-0500 or eec@uci.edu.