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Cytogenetics Technologist Senior II

Brigham and Women's Hospital
United States, Massachusetts, Boston
70 Francis Street (Show on map)
Jun 12, 2025
Summary
The Clinical Cytogenetics Laboratory handles approximately 8,000 specimens per year, performing the following testing: chromosome analysis, fluorescence in-situ hybridization (FISH) and microarray analysis. High complexity testing includes a diverse set of requirements for reporting and specimen handling and follows National Patient Safety Goals, OSHA, CLIA and Joint Commission Regulations. Does this position require Patient Care? No
Essential Functions,
- Serve as a lead technologist of Cytogenetics
-Participate in scheduled technical meetings and assigned CAP proficiency testing
-Provide oversight of technical staff and laboratory workflows in the absence of Supervisor or the Technical Director
-Teach rotating residents and fellows and train new employees when assigned
-Work with Supervisor or Technical Director to perform laboratory audits once every other year
-Provide back-up weekend coverage and holiday coverage

1. Serve as a lead technologist of a service line

2. Log in samples and review submitted clinical data to allow appropriate pre-analytic triage of specimens

3. Perform assigned tissue culture and wet lab duties; troubleshoot workflows or equipment; assist with maintaining equipment, supplies and reagent stocks

4. Demonstrate technical expertise in one or more of the following areas:

a. Chromosome analysis: Initiate and maintain cell cultures using sterile technique; perform all aspects of specimen processing; operate automated cell scanner; analyze metaphases using brightfield microscopy, record raw data, prepare final karyograms and record current ISCN, and/or

b. FISH analysis: Perform all aspects of specimen processing; analyze metaphases or interphase nuclei and record hybridization patterns; capture representative images at the fluorescence microscope workstation, and/or

c. Microarray analysis: Perform all aspects of specimen preparation, including DNA isolation and labeling, hybridization, washing and chip scanning; organize, interpret and annotate genomic data.

5. Provide oversight of technical staff and laboratory workflows in the absence of Supervisor or the Technical Director

6. Perform chart review; provide daily case management and status updates to Supervisor and Technical Director

7. Oversee troubleshooting of assays or equipment; participate in validation of new assays and new equipment; responsible for periodic updates to relevant standard operating protocols

8. Teach rotating residents and fellows and train new employees when assigned

9. Participate in scheduled technical meetings and assigned CAP proficiency testing

10. Work with Supervisor or Technical Director to perform laboratory audits once every other year

11. Provide back-up weekend coverage and holiday coverage; maintain a professional appearance at all times and perform additional assigned duties

Experience
Experience working in a clinical Cytogenetics laboratory 8-10+ years required

Knowledge, Skills and Abilities
- Strong communication and interpersonal skills.
- Productive work habits.
- Manual dexterity and visual acuity.
- Proficient with computers (including use of Microsoft Word, Microsoft Excel, etc.).
- Organized, detail-oriented and able to keep meticulous records.
- Respectful of patient confidentiality.

Physical Requirements

  • Standing Frequently (34-66%)
  • Walking Frequently (34-66%)
  • Sitting Occasionally (3-33%)
  • Lifting Frequently (34-66%) 35lbs+ (w/assisted device)
  • Carrying Frequently (34-66%) 20lbs - 35lbs
  • Pushing Occasionally (3-33%)
  • Pulling Occasionally (3-33%)
  • Climbing Rarely (Less than 2%)
  • Balancing Frequently (34-66%)
  • Stooping Occasionally (3-33%)
  • Kneeling Occasionally (3-33%)
  • Crouching Occasionally (3-33%)
  • Crawling Rarely (Less than 2%)
  • Reaching Frequently (34-66%)
  • Gross Manipulation (Handling) Frequently (34-66%)
  • Fine Manipulation (Fingering) Frequently (34-66%)
  • Feeling Constantly (67-100%)
  • Foot Use Rarely (Less than 2%)
  • Vision - Far Constantly (67-100%)
  • Vision - Near Constantly (67-100%)
  • Talking Constantly (67-100%)
  • Hearing Constantly (67-100%)


The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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